My Dublin based client is looking for a Postdoctoral Researcher to join their team on a 4 year contract. This project will focus on AAV Gene Therapy, IVTmRNA and Protein Biotherapeutic Modality Design and Production.
Position Summary:
The role will look to develop approaches to enhance in vitro transcribed mRNA (IVTmRNAs) design and manufacture, investigating how IVTmRNA sequence, nucleotide modifications and control elements impact the efficiency of translation and protein fidelity in a cell/tissue specific manner.
Responsibilities:
* To devise, undertake appropriate experiments, interpret the findings and devise new approaches to achieve the goals and milestones as described of the project.
* To undertake the mandatory training, reporting, public engagement/outreach activities and any other requirements outlined under the funding agreement for the project.
* Regularly report to the supervisors and consortium, compile data acquired in a form to allow rapid transformation of documented research results into high quality research papers and/or patent applications.
* Attend and present at training activities and research summits and meetings as outlined in the wider programme, including at national/international conferences relevant to the research.
Requirements:
* A PhD in biotechnology, biochemistry, biochemical engineering, genetics, molecular biology, gene therapy, engineering biology, synthetic biology, RNA sequencing or a relevant discipline.
* Training/experience of working with mammalian cells in culture and expression of exogenous genes and recombinant proteins.
* Experience of molecular biology and the designing and generation of expression vectors.
* Training and experience in DNA, mRNA and protein analysis.
Seniority level
Associate
Employment type
Contract
Job function
Science
Industries
Pharmaceutical Manufacturing and Biotechnology Research
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