DESCRIPTIONS of a Preparative Chromatography Specialist
Job Summary: We are seeking an experienced Preparative Chromatography Specialist to join our R&D Department in Swords, Co Dublin. The successful candidate will use their expertise in preparative chromatography to guide the development of purification methods for small molecules from mg to kg scale, including highly potent APIs and intermediates.
Key Responsibilities:
• Collaborate with R&D chemists to scale up development projects in the laboratory, including technology transfer from customers, process development, and process safety assessments.
• Perform analytical and preparative purifications of research materials to support process development.
• Execute achiral and chiral purification of pharmaceutical compounds and isolation of impurities.
• Evaluate and develop separation conditions through solubility, loading, and stability studies at mg to g scale.
• Conducts scaleup demonstrations of separations at multi-g scale.
• Execute early deliveries of 100's g to kg scale in conjunction with our process R&D team.
• Maintain lab presence and be actively involved in lab work.
• Analyze and interpret scientific results.
• Author scientific reports and present work as needed.
• Initiate and champion new technologies' introduction.
• Ensure that the chromatography equipment is qualified and ready for batch manufacture.
Requirements:
• Strong technical background in preparative chromatography in lab and pilot lab scale in Industry of 5 years.
• PhD or Master's degree with specialization in chemistry/engineering or related discipline.
• In-depth knowledge and technical proficiency in preparative chromatography, HPLC, and related techniques.
• Experience with chemical process development, scale-up, and GMP manufacturing with emphasis on chromatographic purification.
• Experience in both low-pressure (flash) as well as high-pressure (prep) chromatography.
• Proven problem-solving capacity.
Additional skills relevant to the role:
• Practical and results-driven.
• Efficient, flexible, and dynamic.
• Integrates and works effectively in a multidisciplinary team.
• Good social and communication skills.
Why choose a career at SK biotek?
A career with purpose and a chance to work with a world-leader in contract development and manufacturing in a fast-paced, dynamic, and growing organisation.